{"id":1801,"date":"2005-10-01T01:00:00","date_gmt":"2005-10-01T00:00:00","guid":{"rendered":"https:\/\/angh.net\/abstracts\/dystrophie-kystique-de-la-paroi-duodenale-associee-a-une-pancreatite-chronique-aspects-cliniques-diagnostiques-et-therapeutiques-de-23-cas\/"},"modified":"2018-10-20T18:39:37","modified_gmt":"2018-10-20T16:39:37","slug":"dystrophie-kystique-de-la-paroi-duodenale-associee-a-une-pancreatite-chronique-aspects-cliniques-diagnostiques-et-therapeutiques-de-23-cas","status":"publish","type":"post","link":"https:\/\/angh.net\/abstracts\/dystrophie-kystique-de-la-paroi-duodenale-associee-a-une-pancreatite-chronique-aspects-cliniques-diagnostiques-et-therapeutiques-de-23-cas\/","title":{"rendered":"DYSTROPHIE KYSTIQUE DE LA PAROI DUODENALE ASSOCIEE A UNE PANCREATITE CHRONIQUE : ASPECTS CLINIQUES , DIAGNOSTIQUES ET THERAPEUTIQUES DE 23 CAS."},"content":{"rendered":"

2005<\/strong><\/p>\n

Vincent Jouannaud (1), Pierre Coutarel (1), Herv\u00e9 Tossou (2), Jacques Butel (3), Ren\u00e9-Louis Vitte (4), Fran\u00e7oise Skizani (5), Martine Blasquez (6), Herv\u00e9 Hagege (7), Christian Bories (2), Philippe Rocher (3), Djamel Belloula (1), Jean Paul Latrive (8), Jean Jacques Meurisse (9), Claude Eugene (4), Marie-Pierre Dellion (1), Jean Fran\u00e7ois Cadranel* (1), Alex Pariente* (11), Association Nationale des h\u00e9pato-Gastroent\u00e9rologues des H\u00f4pitaux g\u00e9n\u00e9raux (ANGH).
\nServices d\u2019H\u00e9pato-Gastroent\u00e9rologie des centres hospitaliers g\u00e9n\u00e9raux de : 1) Creil, 2) Beauvais, 3) Abbeville 4) Poissy, 5) St Denis, 6) Bry Sur Marne, 7) Cr\u00e9teil (Chic), 8) Compi\u00e8gne, 9) Lourdes, 11) Pau 10) Service de Gastroent\u00e9rologie de l\u2019h\u00f4pital Beaujon, Clichy *Coordonnateurs de l\u2019\u00e9tude<\/em><\/p>\n

Gastroent\u00e9rologie <\/strong>– \u00a02005-08-25 –\u00a0CO –<\/p>\n

________________________________<\/p>\n

Objectif – Le but de cette \u00e9tude multicentrique r\u00e9trospective men\u00e9e au sein de l\u2019Association Nationale des H\u00e9pato-Gastroent\u00e9rologues des H\u00f4pitaux G\u00e9n\u00e9raux (ANGH) \u00e9tait de colliger les observations de dystrophie kystique de la paroi duod\u00e9nale sur pancr\u00e9as aberrant chez des patients ayant eu une pancr\u00e9atite chronique (PC) d’origine alcoolique, en mettant l\u2019accent sur l\u2019\u00e9volution clinique apr\u00e8s traitement.
\nPatients et m\u00e9thodes – Les donn\u00e9es provenant des dossiers de 23 patients suivis de janvier 1990 \u00e0 Juillet 2004 dans dix services d\u2019h\u00e9patogastroent\u00e9rologie de centres hospitaliers g\u00e9n\u00e9raux, ont \u00e9t\u00e9 collig\u00e9es. Les caract\u00e9ristiques cliniques, biologiques, endoscopiques et d\u2019imagerie d\u2019une part et les modalit\u00e9s th\u00e9rapeutiques d\u2019autre part sont rapport\u00e9es. Le suivi apr\u00e8s traitement m\u00e9dical, endoscopique et chirurgical est exprim\u00e9 en m\u00e9diane [extr\u00eames].
\nR\u00e9sultats \u2013 Vingt-trois patients (20 hommes) \u00e2g\u00e9s de 45 ans [30-66], ayant une consommation excessive chronique d\u2019alcool, et une pancr\u00e9atite chronique connue (n=14) ou diagnostiqu\u00e9e de fa\u00e7on concomitante (n=9) ont \u00e9t\u00e9 \u00e9tudi\u00e9s. La pr\u00e9sentation clinique \u00e9tait domin\u00e9e par les douleurs abdominales (n=22) et l\u2019amaigrissement (n=16). Dix patients ont eu une \u00e9chographie abdominale, 22 un examen tomodensitom\u00e9trique abdominal, 18 une fibroscopie digestive haute, et 22 une \u00e9cho-endoscopie. L\u2019examen compl\u00e9mentaire le plus performant a \u00e9t\u00e9 l\u2019\u00e9cho-endoscopie, ayant permit le diagnostic de dystrophie kystique sur pancr\u00e9as aberrant de la paroi duod\u00e9nale chez 19 des 23 patients. Vingt patients ont \u00e9t\u00e9 sevr\u00e9s (87%). Le traitement m\u00e9dical et\/ou endoscopique a \u00e9t\u00e9 efficace dans 5 cas sur 16 (31%), dont 1\/7 pour l\u2019octr\u00e9otide (14% d\u2019efficacit\u00e9 \u00e0 long terme, 3 \u00e9checs imm\u00e9diats (43%)) et 0\/2 pour la fenestration endoscopique (\u00e9checs retard\u00e9s). Quatre patients (17%) ont \u00e9t\u00e9 mis en r\u00e9mission par un traitement symptomatique comprenant le sevrage \u00e9thylique. Quatorze patients (61%) ont \u00e9t\u00e9 op\u00e9r\u00e9s, parmi lesquels 78% ont eu une DPC, permettant une r\u00e9mission des sympt\u00f4mes dans 100% des cas. Aucun d\u00e9c\u00e8s n\u2019a \u00e9t\u00e9 constat\u00e9 apr\u00e8s DPC, mais 4 patients (36%) ont eu une insuffisance pancr\u00e9atique endocrine ou exocrine. Le suivi a \u00e9t\u00e9 de 56 mois [2-78] chez les patients qui n\u2019ont pas \u00e9t\u00e9 op\u00e9r\u00e9s (9\/23) et de 47 mois [12-108] chez ceux qui ont \u00e9t\u00e9 op\u00e9r\u00e9s (14\/23). La DPC a permis la disparition des manifestations cliniques \u00e0 long terme dans tous les cas.
\nConclusion \u2013La dystrophie kystique de la paroi duod\u00e9nale compliquant la pancr\u00e9atite chronique d\u2019origine alcoolique en est parfois r\u00e9v\u00e9latrice ; le diagnostic est fait au mieux par l\u2019\u00e9choendoscopie. Le traitement par DPC est le plus efficace et a \u00e9t\u00e9 n\u00e9cessaire chez 11 patients.
\nEtude multicentrique ANGH<\/p>\n","protected":false},"excerpt":{"rendered":"

2005 Vincent Jouannaud (1), Pierre Coutarel (1), Herv\u00e9 Tossou (2), Jacques Butel (3), Ren\u00e9-Louis Vitte (4), Fran\u00e7oise Skizani (5), Martine Blasquez (6), Herv\u00e9 Hagege (7), Christian Bories (2), Philippe Rocher (3), Djamel Belloula (1), Jean Paul Latrive (8), Jean Jacques Meurisse (9), Claude Eugene (4), Marie-Pierre Dellion (1), Jean Fran\u00e7ois Cadranel* (1), Alex Pariente* (11), […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[16],"class_list":["post-1801","post","type-post","status-publish","format-standard","hentry","category-gastroenterologie","tag-16"],"yoast_head":"\nDYSTROPHIE KYSTIQUE DE LA PAROI DUODENALE ASSOCIEE A UNE PANCREATITE CHRONIQUE : ASPECTS CLINIQUES , DIAGNOSTIQUES ET THERAPEUTIQUES DE 23 CAS. - 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