{"id":1887,"date":"2010-10-01T01:00:00","date_gmt":"2010-10-01T00:00:00","guid":{"rendered":"https:\/\/angh.net\/abstracts\/les-18-premiers-mois-de-la-campagne-de-depistage-par-test-hemocult-en-seine-et-marne-resultats-dans-une-unite-dendoscopies-digestives-dhopital-general-et-comparaison-avec-l\/"},"modified":"2018-10-20T18:39:55","modified_gmt":"2018-10-20T16:39:55","slug":"les-18-premiers-mois-de-la-campagne-de-depistage-par-test-hemocult-en-seine-et-marne-resultats-dans-une-unite-dendoscopies-digestives-dhopital-general-et-comparaison-avec-l","status":"publish","type":"post","link":"https:\/\/angh.net\/abstracts\/les-18-premiers-mois-de-la-campagne-de-depistage-par-test-hemocult-en-seine-et-marne-resultats-dans-une-unite-dendoscopies-digestives-dhopital-general-et-comparaison-avec-l\/","title":{"rendered":"Les 18 premiers mois de la campagne de d\u00e9pistage par test Hemocult\u00ae en Seine et Marne : r\u00e9sultats dans une unit\u00e9 d\u2019endoscopies digestives d\u2019h\u00f4pital g\u00e9n\u00e9ral et comparaison avec les autres indications de d\u00e9pistage"},"content":{"rendered":"

2010<\/strong><\/p>\n

Florence Harnois (1), Gilles Macaigne (1), Jean-Fran\u00e7ois Boivin (2), Jean-Paul Desbiez (1), Dorian Dikov (2), Sadek Cheiab (1), Georges Bonyhai (2), Claude Chayette (1). Services d\u2019h\u00e9pato-gastroent\u00e9rologie (1) et d\u2019anatomo-pathologie (2), H\u00f4pital de Lagny-Marne-la-Vall\u00e9e, 77 405 Lagny-sur-Marne Cedex. France.<\/em><\/p>\n

Gastroent\u00e9rologie <\/strong>– \u00a02010-09-02 –\u00a0CO –<\/p>\n

________________________________<\/p>\n

Introduction : La campagne de d\u00e9pistage du cancer colo-rectal par test h\u00e9mocult\u00ae (CCR) a d\u00e9but\u00e9 dans le d\u00e9partement de Seine et Marne en octobre 2008.
\nBut : Les buts de ce travail ont \u00e9t\u00e9 d\u2019\u00e9valuer les r\u00e9sultats du d\u00e9pistage du CCRH dans une unit\u00e9 d\u2019endoscopie d\u2019un h\u00f4pital g\u00e9n\u00e9ral de Seine et Marne durant les 18 premiers mois et de les comparer aux r\u00e9sultats des autres indications de d\u00e9pistage.
\nMalades et m\u00e9thodes : D\u2019octobre 2008 \u00e0 avril 2010, tous les malades adress\u00e9s dans notre centre pour coloscopie de d\u00e9pistage ont \u00e9t\u00e9 inclus. L\u2019indication de la coloscopie de d\u00e9pistage \u00e9tait soit un test Hemocult\u00ae positif, soit un ant\u00e9c\u00e9dent personnel ou familial de tumeur colo-rectale (polype ou cancer). L\u2019ensemble des donn\u00e9es cliniques, endoscopiques et histologiques ont \u00e9t\u00e9 recueillies prospectivement.<\/p>\n

R\u00e9sultats :
\n 486 coloscopies de d\u00e9pistage ont \u00e9t\u00e9 r\u00e9alis\u00e9es, soit 35% de la totalit\u00e9 des coloscopies r\u00e9alis\u00e9es dans l\u2019unit\u00e9 pendant cette p\u00e9riode. La coloscopie \u00e9tait compl\u00e8te dans 98.4% des cas. La population avait un age m\u00e9dian de 72 ans [27-88] et \u00e9tait constitu\u00e9e de 54% d\u2019hommes. L\u2019indication \u00e9tait un test h\u00e9mocult\u00ae positif chez 61 patients (12.5%), un ant\u00e9c\u00e9dent personnel de tumeur colorectale chez 222 patients (45.7%) (cancer dans 16% des cas), un ant\u00e9c\u00e9dent familial au 1er degr\u00e9 chez 180 patients (37,1%) (cancer dans 78% des cas) et un ant\u00e9c\u00e9dent familial au second degr\u00e9 chez 23 patients (4.7%).
\nDans cette cohorte, 7 ad\u00e9nocarcinome, 5 ad\u00e9nome en dysplasie de haut grade (DHG) et 41 ad\u00e9nome>10mm ont \u00e9t\u00e9 diagnostiqu\u00e9s et 1 cas de polypose (sans ant\u00e9c\u00e9dent familial) a \u00e9t\u00e9 d\u00e9tect\u00e9 dans le groupe h\u00e9mocult\u00ae. Les taux de cancer et d\u2019ad\u00e9nome>10mm \u00e9taient significativement plus \u00e9lev\u00e9s dans le groupe H\u00e9mocult\u00ae positif que dans les 3 autres groupes (P<0.001). Les nombres de polype\/colo et d\u2019ad\u00e9nome\/colo \u00e9taient significativement plus \u00e9lev\u00e9s dans le groupe Hemocult\u00ae (p<0.05), les diff\u00e9rences n\u2019\u00e9tant pas significatives entre les 3 autres groupes (tableau 1)
\nLa coloscopie permettait le diagnostic d\u2019au moins un ad\u00e9nome chez 52% des malades du groupe h\u00e9mocult\u00ae et dans 39.3% des malades du groupe ant\u00e9c\u00e9dent familial au premier degr\u00e9 ayant une premi\u00e8re coloscopie ; cette diff\u00e9rence n\u2019\u00e9tait pas significative. Lorsque la coloscopie \u00e9tait anormale, le nombre d\u2019ad\u00e9nome\/colo \u00e9tait significativement sup\u00e9rieur dans le groupe hemocult\u00ae positif que dans le groupe de malades ayant une premi\u00e8re coloscopie pour un ant\u00e9c\u00e9dent familial au premier degr\u00e9 ( 2.7 versus1.9, p= en cours)<\/p>\n

Conclusion :<\/p>\n

les coloscopie de d\u00e9pistage pour H\u00e9mocult\u00ae positif ont repr\u00e9sent\u00e9 12.5% des nos coloscopies de d\u00e9pistage et ont \u00e9t\u00e9 performantes pour le diagnostic des polypes \u00e0 haut risque et de cancer. La coloscopie r\u00e9alis\u00e9e pour test H\u00e9mocult\u00ae positif permettait de diagnostiquer significativement plus de cancer et d\u2019ad\u00e9nome \u00e0 haut risque que dans les autres indications de d\u00e9pistage.<\/p>\n","protected":false},"excerpt":{"rendered":"

2010 Florence Harnois (1), Gilles Macaigne (1), Jean-Fran\u00e7ois Boivin (2), Jean-Paul Desbiez (1), Dorian Dikov (2), Sadek Cheiab (1), Georges Bonyhai (2), Claude Chayette (1). Services d\u2019h\u00e9pato-gastroent\u00e9rologie (1) et d\u2019anatomo-pathologie (2), H\u00f4pital de Lagny-Marne-la-Vall\u00e9e, 77 405 Lagny-sur-Marne Cedex. France. Gastroent\u00e9rologie – \u00a02010-09-02 –\u00a0CO – ________________________________ Introduction : La campagne de d\u00e9pistage du cancer colo-rectal par […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[21],"class_list":["post-1887","post","type-post","status-publish","format-standard","hentry","category-gastroenterologie","tag-21"],"yoast_head":"\nLes 18 premiers mois de la campagne de d\u00e9pistage par test Hemocult\u00ae en Seine et Marne : r\u00e9sultats dans une unit\u00e9 d\u2019endoscopies digestives d\u2019h\u00f4pital g\u00e9n\u00e9ral et comparaison avec les autres indications de d\u00e9pistage - Abstracts des congr\u00e8s de l'ANGH<\/title>\n<meta name=\"description\" content=\"ANGH R\u00e9sum\u00e9s congr\u00e8s H\u00e9patologie Gastroent\u00e9romogie Hepatology Gastroenterology Etudes cliniques Clinical study\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/angh.net\/abstracts\/les-18-premiers-mois-de-la-campagne-de-depistage-par-test-hemocult-en-seine-et-marne-resultats-dans-une-unite-dendoscopies-digestives-dhopital-general-et-comparaison-avec-l\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les 18 premiers mois de la campagne de d\u00e9pistage par test Hemocult\u00ae en Seine et Marne : r\u00e9sultats dans une unit\u00e9 d\u2019endoscopies digestives d\u2019h\u00f4pital g\u00e9n\u00e9ral et comparaison avec les autres indications de d\u00e9pistage - 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