{"id":2421,"date":"2023-01-24T13:46:53","date_gmt":"2023-01-24T12:46:53","guid":{"rendered":"https:\/\/angh.net\/abstracts\/vulnapsy-c-etude-des-facteurs-de-vulnerabilite-psychologique-lies-aux-reinfections-par-le-virus-de-lhepatite-c-resultats-preliminaires\/"},"modified":"2023-01-24T13:46:53","modified_gmt":"2023-01-24T12:46:53","slug":"vulnapsy-c-etude-des-facteurs-de-vulnerabilite-psychologique-lies-aux-reinfections-par-le-virus-de-lhepatite-c-resultats-preliminaires","status":"publish","type":"post","link":"https:\/\/angh.net\/abstracts\/vulnapsy-c-etude-des-facteurs-de-vulnerabilite-psychologique-lies-aux-reinfections-par-le-virus-de-lhepatite-c-resultats-preliminaires\/","title":{"rendered":"VULNAPSY-C, \u00e9tude des facteurs de vuln\u00e9rabilit\u00e9 psychologique li\u00e9s aux r\u00e9infections par le virus de l\u2019h\u00e9patite C : r\u00e9sultats pr\u00e9liminaires"},"content":{"rendered":"

2022<\/strong><\/p>\n

AJ REMY (1), J HERVET (1), J DELMONTE (2)
\n(1)\tCentre Hospitalier de Perpignan
\n(2)\tLaboratoire LPS, Universit\u00e9 d\u2019Aix-Marseille<\/em><\/p>\n

H\u00e9patologie <\/strong>– \u00a02022-04-22 –\u00a0CO –<\/p>\n

________________________________<\/p>\n

Rationnel : dans le monde, la pr\u00e9valence des r\u00e9infections au virus de l\u2019h\u00e9patite C reste extr\u00eamement \u00e9lev\u00e9e chez les usagers de drogue, jusqu\u2019\u00e0 10.5\/100 personnes par an. La litt\u00e9rature internationale sugg\u00e8re que l’intervalle de test pour la vir\u00e9mie r\u00e9currente du VHC (par exemple, toutes les 24 semaines ou 12 semaines) peut jouer un r\u00f4le dans le taux de r\u00e9infection notamment dans les populations \u00e0 risque \u00e9lev\u00e9 de comportements \u00e0 risque (\u00e9change de seringue). A notre connaissance aucune recherche n\u2019a \u00e9valu\u00e9 les facteurs de vuln\u00e9rabilit\u00e9 psychologique (cognitifs, \u00e9motionnels et traits de personnalit\u00e9) majorant les risques de r\u00e9infections dans ces populations. La mise en \u00e9vidence de ces facteurs de vuln\u00e9rabilit\u00e9s pourrait conduire \u00e0 maximiser l\u2019efficacit\u00e9 de groupes de pr\u00e9vention de la rechute par la d\u00e9tection des populations les plus \u00e0 risque. Objectifs : proposer aux patients diff\u00e9rents questionnaires et \u00e9chelles permettant l\u2019\u00e9valuation des processus cognitifs, \u00e9motionnels et des traits de personnalit\u00e9. Le nombre de r\u00e9infections au VHC a \u00e9t\u00e9 \u00e9galement quantifi\u00e9 par quantification de la charge virale C. Notre objectif secondaire a \u00e9t\u00e9 d\u2019\u00e9valuer sur le nombre de r\u00e9infections l\u2019influence du niveau de connaissance des patients concernant les facteurs de risques de contamination ainsi que le niveau de croyances reli\u00e9es \u00e0 la sant\u00e9. Mat\u00e9riel et M\u00e9thodes : auto-administration d\u2019un document comprenant le score de pr\u00e9carit\u00e9 EPICES, des tests cognitifs, un questionnaire d\u2019impulsivit\u00e9 (UPPS), un questionnaire de personnalit\u00e9 BIG 5), un questionnaire du niveau de connaissance des facteurs de risque de contamination et un questionnaire des croyances reli\u00e9es \u00e0 la sant\u00e9. La m\u00e9thodologie choisie a \u00e9t\u00e9 de proposer l\u2019\u00e9tude \u00e0 tous les patients, hommes et femmes, (primo infect\u00e9s et r\u00e9infect\u00e9s), soit lors de la phase diagnostique initiale, soit de la phase de surveillance post traitement, pendant laquelle les recommandations sont de r\u00e9aliser un dosage annuel de la charge virale C. Une approche multisite (CSAPA, CAARUD, prison, squats) a \u00e9t\u00e9 utilis\u00e9e pour maximiser le recrutement. Le temps de remplissage a \u00e9t\u00e9 estim\u00e9 entre 30 et 45 minutes. Le recueil des donn\u00e9es m\u00e9dicosociales personnes a \u00e9t\u00e9 effectu\u00e9 parall\u00e8lement par un infirmier de notre \u00e9quipe.
\nR\u00e9sultats : 30 malades gu\u00e9ris sans r\u00e9infection et 16 malades r\u00e9infect\u00e9s par le HCV par usage de drogues apr\u00e8s gu\u00e9rison ont rempli le questionnaire ; 85% d\u2019hommes, \u00e2ge moyen 34 ans. Les patients r\u00e9infect\u00e9s sont plus jeunes, de niveau \u00e9ducatif plus bas, plus souvent sans domicile fixe et ayant des ant\u00e9c\u00e9dents de maladies psychiatriques que les patients sans r\u00e9infection. Les autres facteurs favorisant la r\u00e9infection seront pr\u00e9sent\u00e9s lors du congr\u00e8s. Chez les patients r\u00e9infect\u00e9s, les r\u00e9sultats \u00e9taient les suivants : Plus le patient pense qu\u2019il est responsable de sa maladie plus il est impulsif (dimension urgence impulsivit\u00e9 \u00e9motionnelle). Plus le patient \u00e0 conscience des cons\u00e9quences de sa maladie plus il est impulsif (dimension urgence impulsivit\u00e9 \u00e9motionnelle). Plus le patient est impulsif (score total + dimension urgence impulsivit\u00e9 \u00e9motionnelle), plus il pr\u00e9sente un score \u00e9lev\u00e9 de n\u00e9vrosisme (trait de personnalit\u00e9 n\u00e9gativiste). Moins le patient exprime le trait de personnalit\u00e9 \u00ab conscience \u00bb, plus il pr\u00e9sente un manque de pers\u00e9v\u00e9ration de ses comportements (impulsivit\u00e9 cognitive). Plus le patient exprime le trait de personnalit\u00e9 \u00ab ouverture \u00bb, plus il met en place des comportements impulsifs type recherche de sensations.
\nPlus le patient participe aux ateliers r\u00e9duction des risques, plus il se sent responsable de sa maladie, plus il a conscience des cons\u00e9quences de sa maladie et plus il a de pens\u00e9es magiques concernant sa contamination (exemple item : \u00ab le simple fait de voir quelqu\u2019un de malade est suffisant pour me rendre malade aussi \u00bb). Il n\u2019y avait pas de corr\u00e9lation avec le score de pr\u00e9carit\u00e9 EPICES. Les r\u00e9sultats concernant les patients primo-contamin\u00e9s seront d\u00e9taill\u00e9s lors du congr\u00e8s. Conclusion : il existe des facteurs de vuln\u00e9rabilit\u00e9 psychologique et sociale favorisant la r\u00e9infection HCV par usage de drogues. Des actions cibl\u00e9es sur les patients les plus \u00e0 risque sont indispensables pour contribuer \u00e0 l\u2019\u00e9limination du VHC en France.<\/p>\n

R\u00e9f\u00e9rences
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\n2.\tGountas, I.; Sypsa, V.; Blach, S.; Razavi, H. & Hatzakis, A., (2018). HCV elimination among people who inject drugs. Modelling pre- and post\u2013WHO elimination era. PLoS ONE, 13, e0202109.
\n3.\tMuller, A.; Vlahov, D.; Akiyama, M.J. & Kurth A., (2020). Hepatitis C Reinfection in People Who Inject Drugs in Resource-Limited Countries: A Systematic Review and Analysis. Int. J. Environ. Res. Public Health. 9;17(14):4951. doi: 10.3390\/ijerph17144951
\n4.\tRossi, C.; Butt, Z.A.; Wong, S.; Buxton, J.; Islam, N.; Yu, A.; Darvishian, M.; Gilbert, M.; Wong, J.; (2018). BC Hepatitis Testers Cohort Team. Hepatitis C virus reinfection after successful treatment with direct-acting antiviral therapy in a large population-based cohort. J. Hepatol. 2018, 69, 1007\u20131014.
\n5.\tRemy AJ, Bouchkira H, Hervet J, Happiette A, Wenger H. Mobile Hepatitis Team: a new pathway of HCV outreach care, since screening to treatment. Gut and Gastroenterology 2019, 2: 1-6.<\/p>\n","protected":false},"excerpt":{"rendered":"

2022 AJ REMY (1), J HERVET (1), J DELMONTE (2) (1) Centre Hospitalier de Perpignan (2) Laboratoire LPS, Universit\u00e9 d\u2019Aix-Marseille H\u00e9patologie – \u00a02022-04-22 –\u00a0CO – ________________________________ Rationnel : dans le monde, la pr\u00e9valence des r\u00e9infections au virus de l\u2019h\u00e9patite C reste extr\u00eamement \u00e9lev\u00e9e chez les usagers de drogue, jusqu\u2019\u00e0 10.5\/100 personnes par an. La litt\u00e9rature […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[3],"tags":[35],"class_list":["post-2421","post","type-post","status-publish","format-standard","hentry","category-hepatologie","tag-35"],"yoast_head":"\nVULNAPSY-C, \u00e9tude des facteurs de vuln\u00e9rabilit\u00e9 psychologique li\u00e9s aux r\u00e9infections par le virus de l\u2019h\u00e9patite C : r\u00e9sultats pr\u00e9liminaires - Abstracts des congr\u00e8s de l'ANGH<\/title>\n<meta name=\"description\" content=\"ANGH R\u00e9sum\u00e9s congr\u00e8s H\u00e9patologie Gastroent\u00e9romogie Hepatology Gastroenterology Etudes cliniques Clinical study\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/angh.net\/abstracts\/vulnapsy-c-etude-des-facteurs-de-vulnerabilite-psychologique-lies-aux-reinfections-par-le-virus-de-lhepatite-c-resultats-preliminaires\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"VULNAPSY-C, \u00e9tude des facteurs de vuln\u00e9rabilit\u00e9 psychologique li\u00e9s aux r\u00e9infections par le virus de l\u2019h\u00e9patite C : r\u00e9sultats pr\u00e9liminaires - 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