{"id":2545,"date":"2023-09-21T15:48:30","date_gmt":"2023-09-21T13:48:30","guid":{"rendered":"https:\/\/angh.net\/abstracts\/?p=2545"},"modified":"2023-09-21T15:48:31","modified_gmt":"2023-09-21T13:48:31","slug":"impact-of-the-pandemic-covid-19-in-the-diagnosis-and-management-of-colorectal-cancer-in-2020-in-portuguese-hospitals-eticc-study-portuguese-results","status":"publish","type":"post","link":"https:\/\/angh.net\/abstracts\/impact-of-the-pandemic-covid-19-in-the-diagnosis-and-management-of-colorectal-cancer-in-2020-in-portuguese-hospitals-eticc-study-portuguese-results\/","title":{"rendered":"Impact of the pandemic COVID-19 in the diagnosis and management of colorectal cancer in 2020 in Portuguese hospitals \u2013 ETICC study \u2013 Portuguese results"},"content":{"rendered":"\n<p><em>B\u00e1rbara Abreu, Cristiana Sequeira, T\u00e2nia Gago, Cristina Teixeira, Pierre Lahmek, Marine Besnard, BrunoLesgourgues, Maria Ana Rafael. Portugal, France.<\/em><\/p>\n\n\n\n<p>This is a Portuguese substudy of the French retrospective multicentric study ETICC (<em>Etude de l\u2019Impact de la pand\u00e9mie COVID-19 sur le diagnostic et la prise en charge du Cancer Colorectal<\/em>) coordinated by the <em>Association Nationale des Gastroent\u00e9rologues des H\u00f4pitaux G\u00e9n\u00e9raux<\/em>.The French study included 11 centers, with a total of 961 patients. In Portugal, 4 centers were included.<\/p>\n\n\n\n<p>Patients included in the control group had a diagnosis of CRC made between the 1<sup>st<\/sup> January 2019 and the 29<sup>th<\/sup> February 2020 and patients included in the COVID group had a diagnosis performed between the 1<sup>st<\/sup> March 2020 and the 28<sup>th<\/sup> February 2021.<\/p>\n\n\n\n<p>Data were collected regarding patient\u2019s characteristics and tumor\u2019s characteristics. Dates of first medical consultation concerning CRC, histological diagnosis, surgical resection, neodjuvant treatment, adjuvant or palliative chemotherapy were also collected. It was registered if there was a perception of a delay in the diagnosis or treatment of the CRC. To compare the \u201ccontrol\u201d and \u201cCOVID\u201d groups, non-parametric tests were used to compare quantitative variables and chi-square and the conditional independence Mantel\u2013Haenszel test were used to compare qualitative variables. &nbsp;<\/p>\n\n\n\n<p><strong>Results<\/strong><\/p>\n\n\n\n<p>We included 766 patients, 496 in the control group and 270 in the COVID group, with similar median ages (70 years-old, IQR 58-82) and sex distribution (60% men) between groups. Concerning the staging of the CRC at the time of diagnosis, no statistically difference was found between groups (p=0.770). In the control group 25% of patients were asymptomatic at the time of diagnosis, whereas in the COVID group only 8.4% were asymptomatic (p&lt;0.001). There was also a significant decrease in diagnosis after a positive fecal immunochemical test (FIT): 20.8% in the control group and 11.3% in the COVID group (p=0.002). In France, no significant decrease in CRC diagnosis in asymptomatic patients was found. 31.7% and 41.1% of patients initiated their follow-up at the hospital after going to the emergency room in the control and COVID groups, respectively, and 53.6% and 48.5% after consulting their general practitioner (p=0.020). The rate of complications at the time of diagnosis has increased, but without statistically significance, from 17.8% in the control group to 23.7% in the COVID group (p=0.050). Abdominal occlusion was the principal complication. In France, there was no significant difference in the rate of all complications or abdominal occlusion at the time of diagnosis.<\/p>\n\n\n\n<p>A delay in the diagnosis and management was inferred in 16.6% of patients in the control group and in 33.6% in the COVID group (p&lt;0.001). Time between the beginning of symptoms and first medical consultation significantly increased, from a median of 50 days in the control group to 64 days in the COVID group (p&lt;0.001). On the contrary, time between histological diagnosis and tumor resection has decreased from a median of 65 days in the control group to 39 days in the COVID group (p&lt;0.001). Time between histological diagnosis and neodjuvant treatment was not statistically different, as well as time between histological diagnosis and palliative chemotherapy. Time from CRC resection and adjuvant treatment has significantly decreased from 54 days in the control group to 43 days in the COVID group (p=0.001). In France, the only statistically significant interval difference was between CRC histological diagnosis and resection, which, similarly to what happened in Portugal, has decreased from 29.5 in the control group to 23 days in the COVID group (p=0.013).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>B\u00e1rbara Abreu, Cristiana Sequeira, T\u00e2nia Gago, Cristina Teixeira, Pierre Lahmek, Marine Besnard, BrunoLesgourgues, Maria Ana Rafael. Portugal, France. This is a Portuguese substudy of the French retrospective multicentric study ETICC (Etude de l\u2019Impact de la pand\u00e9mie COVID-19 sur le diagnostic et la prise en charge du Cancer Colorectal) coordinated by the Association Nationale des Gastroent\u00e9rologues [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-2545","post","type-post","status-publish","format-standard","hentry","category-gastroenterologie"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Impact of the pandemic COVID-19 in the diagnosis and management of colorectal cancer in 2020 in Portuguese hospitals \u2013 ETICC study \u2013 Portuguese results - 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